From a biological idea to a measurable question
In multiple sclerosis, injury to myelin and nerve cells can affect neurological function. The Green Lab studies biological markers of repair and progression to support the development and evaluation of potential reparative therapies.
Connecting laboratory and clinical research
The lab’s work spans biological validation and clinical trials. ReCOVER examines clemastine in acute optic neuritis; ReVIVE uses MRI measurements in people with multiple sclerosis.
These are research studies of an investigational use. Their inclusion here does not establish clemastine as an approved treatment for myelin repair.

Selected evidence
Myelin repair
Clemastine fumarate promotes myelin repair in a nonhuman primate model of demyelination characterized by absent spontaneous remyelination.
Read publication on PubMedClinical trials