University of California San FranciscoNeuroimmunology & Glial Biology

Green Lab · UCSF

Understand injury.
Discover paths
to repair.

We study how neurological disease damages the nervous system—and how to measure, protect, and restore its function.

Fluorescence microscopy from the Green Lab image collection, with red and green cellular structures and blue points of fluorescence
A closer look at the biology of repairGREEN LAB IMAGE COLLECTION
From biological discovery
to clinical investigation.

Our work connects biomarkers, the visual system, and myelin repair to advance research in multiple sclerosis and related neurological conditions.

Our research

Three connected ways
to ask what comes next.

Discover our approach
MOLECULES & MEASUREMENT

Biomarkers of injury

Developing sensitive ways to measure nervous system injury and follow changes over time.

Explore biomarker research
BIOLOGY & REPAIR

Myelin repair

Investigating remyelination: restoring the protective insulation around nerve fibers.

Explore myelin repair
VISION & FUNCTION

The visual system

Using the retina and visual pathways to understand neurological injury and measure repair.

Explore visual system research
A Green Lab researcher examining a sample vial at the laboratory bench
Inside the Green Lab · UCSF Mission Bay

The people behind the questions

Careful science.
Collaborative by nature.

Led by Ari Green, MD, the lab brings laboratory research and clinical investigation together to understand nervous system injury and evaluate potential approaches to repair.

Meet the lab

Clinical investigation

Moving research forward,
with participants.

View clinical studies
UCSF lists as accepting participants*

ReCOVER

Clemastine and potential myelin repair after acute optic neuritis.

Phase 2 · NCT02521311

Explore ReCOVER
UCSF lists as accepting participants*

ReVIVE

Using MRI to assess potential myelin repair in multiple sclerosis.

Phase 1/2 · NCT05359653

Explore ReVIVE

*Status checked October 6, 2026. The study team confirms current availability and eligibility.

Selected publications

Questions explored.
Knowledge shared.

Browse selected publications
2026

Myelin repair

Clemastine fumarate promotes myelin repair in a nonhuman primate model of demyelination characterized by absent spontaneous remyelination.

Sarrazin N, et al.
PNAS · 123(8):e2520161123

Read publication on PubMed
2024

Visual system

Synaptic injury in the inner plexiform layer of the retina is associated with progression in multiple sclerosis.

Cordano C, et al.
Cell Reports Medicine · 5(4):101490

Read publication on PubMed

Connect with us

Better questions. Shared discovery.

Contact the lab