Ari Green, MD

Chief of the Division of Neuroimmunology and Glial Biology
Medical Director of the UCSF MS and Neuroinflammation Center
Neurology

Dr. Ari J Green is the Chief of the Division of Neuroimmunology and Glial Biology in the Department of Neurology at the University of California at San Francisco. His team consists of more than 20 laboratories and groups dedicated to discovering the causes of Multiple Sclerosis and related disorders; and to developing treatments as well as cures for these conditions. Dr. Green is also Medical Director of the UCSF MS and Neuroinflammation Center – one of the largest clinics of its kind in the United States with a broad focus on caring for patients with conditions in which immune dysregulation  or inflammation play an important role. The clinic seeks to provide comprehensive, patient-centered care for people living with these diseases with a wide variety of ancillary services for diagnosis, monitoring and supporting patients and their families. Dr. Green’s laboratory is dedicated to the biological validation of potential biomarkers intended to measure remyelination and repair (as well as progression) in MS as a means to accelerate clinical trials for reparative treatments. His major scientific contributions include directing the first successful phase II clinical trial of a remyelinating agent for MS, developing methods for monitoring myelin repair, detailing the histopathological changes in the retina seen in MS, and describing the role of progranulin in the retina along with discovering a previously unknown retinal phenotype in progranulin-related frontotemporal dementia. His lab maintains an active interest in the developing and validating biomarkers for neurodegenerative disease generally and inflammatory diseases of the central nervous system in particular.  He also co-directs the Program in Remyelination and Repair with Dr. Jonah Chan as well as the Neurodiagnostics Center in the Department of Neurology. 

Dr. Green completed medical school at Duke University School of Medicine in 2001 (during which time he had a Howard Hughes Medical Institute predoctoral fellowship with Drs. Jorge Oksenberg and Stephen L Hauser) and Internship in the Department of Medicine at UCSF in 2002. He completed Residency training at UCSF including Chief Residency in Neurology and post residency fellowships in Neuroimmunology under Dr. Stephen Hauser and Neuro-ophthalmology under Drs. William F. Hoyt and Kimberly Cockerham at UCSF. He then had a visiting fellowship at Queen’s University Belfast under Dame Ingrid Allen in Neuropathology.  He was named the first AAN/NMSS Clinician Science Fellow in 2005 and received a Howard Hughes Clinician Scientist award from HHMI. He was named as the Debbie and Andy Rachleff Distinguished Professor of Neurology in 2009 and joined the Department of Ophthalmology at UCSF in 2011. He was a Harry Weaver Neuroscience Scholar and has served as Associate Editor for JAMA Neurology since 2017.

Publications: 

Remyelination protects neurons from DLK-mediated neurodegeneration.

Nature communications

Duncan GJ, Ingram SD, Emberley K, Hill J, Cordano C, Abdelhak A, McCane M, Jenks JE, Jabassini N, Ananth K, Ferrara SJ, Stedelin B, Sivyer B, Aicher SA, Scanlan TS, Watkins TA, Mishra A, Nelson JW, Green AJ, Emery B

Targeting the muscarinic M1 receptor with a selective, brain-penetrant antagonist to promote remyelination in multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America

Poon MM, Lorrain KI, Stebbins KJ, Edu GC, Broadhead AR, Lorenzana AJ, Roppe JR, Baccei JM, Baccei CS, Chen AC, Green AJ, Lorrain DS, Chan JR

Individual Prognostication of Disease Activity and Disability Worsening in Multiple Sclerosis With Retinal Layer Thickness z Scores.

Neurology(R) neuroimmunology & neuroinflammation

Lin TY, Motamedi S, Asseyer S, Chien C, Saidha S, Calabresi PA, Fitzgerald KC, Samadzadeh S, Villoslada P, Llufriu S, Green AJ, Preiningerova JL, Petzold A, Leocani L, Garcia-Martin E, Oreja-Guevara C, Outteryck O, Vermersch P, Balcer LJ, Kenney R, Albrecht P, Aktas O, Costello F, Frederiksen J, Uccelli A, Cellerino M, Frohman EM, Frohman TC, Bellmann-Strobl J, Schmitz-Hübsch T, Ruprecht K, Brandt AU, Zimmermann HG, Paul F

Minimum effective dose of clemastine in a mouse model of preterm white matter injury.

Pediatric research

Odell EP, Jabassini N, Schniedewind B, Pease-Raissi SE, Frymoyer A, Christians U, Green AJ, Chan JR, Ostrem BEL

Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency.

Science translational medicine

Pluvinage JV, Ngo T, Fouassier C, McDonagh M, Holmes BB, Bartley CM, Kondapavulur S, Hurabielle C, Bodansky A, Pai V, Hinman S, Aslanpour A, Alvarenga BD, Zorn KC, Zamecnik C, McCann A, Asencor AI, Huynh T, Browne W, Tubati A, Haney MS, Douglas VC, Louine M, Cree BAC, Hauser SL, Seeley W, Baranzini SE, Wells JA, Spudich S, Farhadian S, Ramachandran PS, Gillum L, Hales CM, Zikherman J, Anderson MS, Yazdany J, Smith B, Nath A, Suh G, Flanagan EP, Green AJ, Green R, Gelfand JM, DeRisi JL, Pleasure SJ, Wilson MR

Safety and efficacy of inebilizumab for the treatment of neuromyelitis optica spectrum disorder: end-of-study results from the open-label period of the N-MOmentum trial.

The Lancet. Neurology

Cree BAC, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk DM, Fujihara K, Paul F, Cutter GR, Marignier R, Green AJ, Aktas O, Hartung HP, She D, Rees W, Smith M, Cimbora D, Katz E, Bennett JL, N-MOmentum study investigators

Targeting complement C3a receptor resolves mitochondrial hyperfusion and subretinal microglial activation in progranulin-deficient frontotemporal dementia.

bioRxiv : the preprint server for biology

Tan LX, Oertel FC, Cheng A, Cobigo Y, Keihani A, Bennett DJ, Abdelhak A, Montes SC, Chapman M, Chen RY, Cordano C, Ward ME, Casaletto K, Kramer JH, Rosen HJ, Boxer A, Miller BL, Green AJ, Elahi FM, Lakkaraju A

The Study of Remyelinating Therapies in Multiple Sclerosis: Visual Outcomes as a Window Into Repair.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

Zuroff LR, Green AJ

An autoantibody signature predictive for multiple sclerosis.

Nature medicine

Zamecnik CR, Sowa GM, Abdelhak A, Dandekar R, Bair RD, Wade KJ, Bartley CM, Kizer K, Augusto DG, Tubati A, Gomez R, Fouassier C, Gerungan C, Caspar CM, Alexander J, Wapniarski AE, Loudermilk RP, Eggers EL, Zorn KC, Ananth K, Jabassini N, Mann SA, Ragan NR, Santaniello A, Henry RG, Baranzini SE, Zamvil SS, Sabatino JJ, Bove RM, Guo CY, Gelfand JM, Cuneo R, von Büdingen HC, Oksenberg JR, Cree BAC, Hollenbach JA, Green AJ, Hauser SL, Wallin MT, DeRisi JL, Wilson MR

Synaptic injury in the inner plexiform layer of the retina is associated with progression in multiple sclerosis.

Cell reports. Medicine

Cordano C, Werneburg S, Abdelhak A, Bennett DJ, Beaudry-Richard A, Duncan GJ, Oertel FC, Boscardin WJ, Yiu HH, Jabassini N, Merritt L, Nocera S, Sin JH, Samana IP, Condor Montes SY, Ananth K, Bischof A, UCSF MS EPIC Team, Nourbakhsh B, Hauser SL, Cree BAC, Emery B, Schafer DP, Chan JR, Green AJ

Minimum Effective Dose of Clemastine in a Mouse Model of Preterm White Matter Injury.

bioRxiv : the preprint server for biology

Odell E, Jabassini N, Schniedewind B, Pease-Raissi SE, Frymoyer A, Christians U, Green AJ, Chan JR, Ostrem BEL

Scientific commentary on: "Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies".

Acta neuropathologica

Oertel FC, Casillas D, Cobigo Y, Condor Montes S, Heuer HW, Chapman M, Beaudry-Richard A, Reinsberg H, Abdelhak A, Cordano C, Boeve BF, Dickerson BC, Grossman M, Huey E, Irwin DJ, Litvan I, Pantelyat A, Tartaglia MC, Vandevrede L, Boxer A, Green AJ

Identification and In Vivo Evaluation of Myelination Agent PIPE-3297, a Selective Kappa Opioid Receptor Agonist Devoid of β-Arrestin-2 Recruitment Efficacy.

ACS chemical neuroscience

Schrader TO, Lorrain KI, Bagnol D, Edu GC, Broadhead A, Baccei C, Poon MM, Stebbins KJ, Xiong Y, Lorenzana AO, Chan JR, Green AJ, Lorrain DS, Chen A

Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis.

JAMA neurology

Abdelhak A, Benkert P, Schaedelin S, Boscardin WJ, Cordano C, Oechtering J, Ananth K, Granziera C, Melie-Garcia L, Montes SC, Beaudry-Richard A, Achtnichts L, Oertel FC, Lalive PH, Leppert D, Müller S, Henry RG, Pot C, Matthias A, Salmen A, Oksenberg JR, Disanto G, Zecca C, D'Souza M, Du Pasquier R, Bridel C, Gobbi C, Kappos L, Hauser SL, Cree BAC, Kuhle J, Green AJ, UCSF, MS EPIC, and the SMSC Study Teams

Patient-reported outcome parameters and disability worsening in progressive multiple sclerosis.

Multiple sclerosis and related disorders

Abdelhak A, Antweiler K, Kowarik MC, Senel M, Havla J, Zettl UK, Kleiter I, Hoshi MM, Skripuletz T, Haarmann A, Stahmann A, Huss A, Gingele S, Krumbholz M, Selge C, Friede T, Ludolph AC, Overell J, Koendgen H, Clinch S, Wang Q, Ziemann U, Hauser SL, Kümpfel T, Green AJ, Tumani H

Remyelination protects neurons from DLK-mediated neurodegeneration.

bioRxiv : the preprint server for biology

Duncan GJ, Ingram SD, Emberley K, Hill J, Cordano C, Abdelhak A, McCane M, Jabassini N, Ananth K, Ferrara SJ, Stedelin B, Sivyer B, Aicher SA, Scanlan T, Watkins TA, Mishra A, Nelson J, Green AJ, Emery B

Retinal Changes After Acute and Late Optic Neuritis in Aquaporin-4 Antibody Seropositive NMOSD.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

Oertel FC, Zimmermann HG, Motamedi S, Bereuter C, Asseyer ES, Chien C, Marignier R, Cobo-Calvo A, Leocani L, Pisa M, Radaelli M, Villoslada P, Sanchez-Dalmau B, Martinez-Lapiscina EH, Lana-Peixoto MA, Fontenelle MA, Aktas O, Ringelstein M, Albrecht P, Green AJ, Yeaman MR, Smith TJ, Cook L, Paul F, Brandt AU

Attack adjudication in neuromyelitis optica spectrum disorder: Substantiation of criteria by magnetic resonance imaging and biomarkers in N-MOmentum.

Multiple sclerosis (Houndmills, Basingstoke, England)

Weinshenker BG, Wingerchuk DM, Green AJ, Bennett JL, Kim HJ, Pittock SJ, Fujihara K, Paul F, Cutter G, Marignier R, Aktas O, Hartung HP, She D, Smith M, Rees W, Patterson K, Cimbora D, Katz E, Cree BA

Imaging immunomodulatory treatment responses in a multiple sclerosis mouse model using hyperpolarized 13C metabolic MRI.

Communications medicine

Guglielmetti C, Cordano C, Najac C, Green AJ, Chaumeil MM

A Predictive Autoantibody Signature in Multiple Sclerosis.

medRxiv : the preprint server for health sciences

Zamecnik CR, Sowa GM, Abdelhak A, Dandekar R, Bair RD, Wade KJ, Bartley CM, Tubati A, Gomez R, Fouassier C, Gerungan C, Alexander J, Wapniarski AE, Loudermilk RP, Eggers EL, Zorn KC, Ananth K, Jabassini N, Mann SA, Ragan NR, Santaniello A, Henry RG, Baranzini SE, Zamvil SS, Bove RM, Guo CY, Gelfand JM, Cuneo R, von Büdingen HC, Oksenberg JR, Cree BA, Hollenbach JA, Green AJ, Hauser SL, Wallin MT, DeRisi JL, Wilson MR

Prognostic performance of blood neurofilament light chain protein in hospitalized COVID-19 patients without major central nervous system manifestations: an individual participant data meta-analysis.

Journal of neurology

Abdelhak A, Barba L, Romoli M, Benkert P, Conversi F, D'Anna L, Masvekar RR, Bielekova B, Prudencio M, Petrucelli L, Meschia JF, Erben Y, Furlan R, De Lorenzo R, Mandelli A, Sutter R, Hert L, Epple V, Marastoni D, Sellner J, Steinacker P, Aamodt AH, Heggelund L, Dyrhol-Riise AM, Virhammar J, Fällmar D, Rostami E, Kumlien E, Blennow K, Zetterberg H, Tumani H, Sacco S, Green AJ, Otto M, Kuhle J, Ornello R, Foschi M, Abu-Rumeileh S

MWF of the corpus callosum is a robust measure of remyelination: Results from the ReBUILD trial.

Proceedings of the National Academy of Sciences of the United States of America

Caverzasi E, Papinutto N, Cordano C, Kirkish G, Gundel TJ, Zhu A, Akula AV, Boscardin WJ, Neeb H, Henry RG, Chan JR, Green AJ

Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.

The Journal of clinical investigation

Kapell H, Fazio L, Dyckow J, Schwarz S, Cruz-Herranz A, Mayer C, Campos J, D Este E, M?bius W, Cordano C, Pr?bstel AK, Gharagozloo M, Zulji A, Narayanan Naik V, Delank AK, Cerina M, M?ntefering T, Lerma-Martin C, Sonner JK, Sin JH, Disse P, Rychlik N, Sabeur K, Chavali M, Srivastava R, Heidenreich M, Fitzgerald KC, Seebohm G, Stadelmann C, Hemmer B, Platten M, Jentsch TJ, Engelhardt M, Budde T, Nave KA, Calabresi PA, Friese MA, Green AJ, Acuna C, Rowitch DH, Meuth SG, Schirmer L

Visually Evoked Potential as Prognostic Biomarker for Neuroaxonal Damage in Multiple Sclerosis From a Multicenter Longitudinal Cohort.

Neurology(R) neuroimmunology & neuroinflammation

Oertel FC, Kr?mer J, Motamedi S, Keihani A, Zimmermann HG, Dimitriou NG, Condor-Montes S, Bereuter C, Cordano C, Abdelhak A, Trip A, Aktas O, Meuth SG, Wiendl H, Ruprecht K, Bellmann-Strobl J, Paul F, Petzold A, Brandt AU, Albrecht P, Green AJ

Diagnostic value of intereye difference metrics for optic neuritis in aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorders.

Journal of neurology, neurosurgery, and psychiatry

Oertel FC, Zimmermann HG, Motamedi S, Chien C, Aktas O, Albrecht P, Ringelstein M, Dcunha A, Pandit L, Martinez-Lapiscina EH, Sanchez-Dalmau B, Villoslada P, Palace J, Roca-Fern?ndez A, Leite MI, Sharma SM, Leocani L, Pisa M, Radaelli M, Lana-Peixoto MA, Fontenelle MA, Havla J, Ashtari F, Kafieh R, Dehghani A, Pourazizi M, Marignier R, Cobo-Calvo A, Asgari N, Jacob A, Huda S, Mao-Draayer Y, Green AJ, Kenney R, Yeaman MR, Smith TJ, Cook L, Brandt AU, Paul F, Petzold A

Tailoring a home-based, multidisciplinary deprescribing intervention through clinicians and community-dwelling older adults.

Journal of the American Geriatrics Society

Lee JW, Boyd CM, Leff B, Green A, Hornstein E, LaFave S, Seau Q, Nkodo A, Kachur S, Williams N, Riser T, Szanton SL

Validating visual evoked potentials as a preclinical, quantitative biomarker for remyelination efficacy.

Brain : a journal of neurology

Cordano C, Sin JH, Timmons G, Yiu HH, Stebbins K, Guglielmetti C, Cruz-Herranz A, Xin W, Lorrain D, Chan JR, Green AJ

Differences in Age-Related Retinal and Cortical Atrophy Rates in Multiple Sclerosis.

Neurology

Cordano C, Nourbakhsh B, Yiu HH, Papinutto N, Caverzasi E, Abdelhak AC, Cosima C Oertel F, Beaudry-Richard A, Santaniello A, Sacco S, Bennett DJ, Gomez A, Sigurdson CJ, Hauser SL, Magliozzi R, Campbell Cree BA, Henry RG, Green AJ

Longitudinal retinal changes in MOGAD.

Annals of neurology

Oertel FC, Sotirchos ES, Zimmermann HG, Motamedi S, Specovius S, Asseyer ES, Chien C, Cook L, Vasileiou E, Filippatou A, Calabresi PA, Saidha S, Pandit L, D'Cunha A, Outteryck O, Zéphir H, Pittock S, Flanagan EP, Bhatti MT, Rommer PS, Bsteh G, Zrzavy T, Kuempfel T, Aktas O, Ringelstein M, Albrecht P, Ayzenberg I, Pakeerathan T, Knier B, Aly L, Asgari N, Soelberg K, Marignier R, Tilikete CF, Calvo AC, Villoslada P, Sanchez-Dalmau B, Martinez-Lapiscina EH, Llufriu S, Green AJ, Yeaman MR, Smith TJ, Brandt AU, Chen J, Paul F, Havla J, with the GJCF International Clinical Consortium for NMOSD and the CROCTINO study group

Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology.

Alzheimer's & dementia (Amsterdam, Netherlands)

Abdelhak A, Solomon I, Montes SC, Saias A, Cordano C, Asken B, Fonseca C, Oertel FC, Arfanakis K, Staffaroni AM, Kramer JH, Geschwind M, Miller BL, Elahi FM, Green AJ

Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis.

Journal of neurology, neurosurgery, and psychiatry

Abdelhak A, Cordano C, Boscardin WJ, Caverzasi E, Kuhle J, Chan B, Gelfand JM, Yiu HH, Oertel FC, Beaudry-Richard A, Condor Montes S, Oksenberg JR, Lario Lago A, Boxer A, Rojas-Martinez JC, Elahi FM, Chan JR, Green AJ

Transitioning From S1P Receptor Modulators to B Cell-Depleting Therapies in Multiple Sclerosis: Clinical, Radiographic, and Laboratory Data.

Neurology(R) neuroimmunology & neuroinflammation

Rowles WM, Hsu WY, McPolin K, Li A, Merrill S, Guo CY, Green AJ, Gelfand JM, Bove RM

Reply to "Interpretation of Longitudinal Changes of the Inner Nuclear Layer in MS".

Annals of neurology

Cordano C, Yiu HH, Abdelhak A, Beaudry-Richard A, Oertel FC, Green AJ

Reply to "Spinal cord atrophy is a preclinical marker of progressive MS".

Annals of neurology

Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, Mallott JM, Asteggiano C, Sacco S, Gundel TJ, Zhao C, Stern WA, Caverzasi E, Zhou Y, Gomez R, Ragan NR, Santaniello A, Zhu AH, Juwono J, Bevan CJ, Bove RM, Crabtree E, Gelfand JM, Goodin DS, Graves JS, Green AJ, Oksenberg JR, Waubant E, Wilson MR, Zamvil SS, University of CaliforniaSan Francisco MS-EPIC Team, Cree BA, Hauser SL, Henry RG

A hormonal therapy for menopausal women with MS: A phase Ib/IIa randomized controlled trial.

Multiple sclerosis and related disorders

Bove R, Anderson A, Rowles W, Rankin KA, Hills NK, Carleton M, Cooper J, Cree BAC, Gelfand JM, Graves JS, Henry RG, Krysko KM, Rush G, Zamvil SS, Joffe H, Chan JR, Green AJ

Blood GFAP as an emerging biomarker in brain and spinal cord disorders.

Nature reviews. Neurology

Abdelhak A, Foschi M, Abu-Rumeileh S, Yue JK, D'Anna L, Huss A, Oeckl P, Ludolph AC, Kuhle J, Petzold A, Manley GT, Green AJ, Otto M, Tumani H

Characterizing Fixational Eye Motion Variance Over Time as Recorded by the Tracking Scanning Laser Ophthalmoscope.

Translational vision science & technology

Condor Montes SY, Bennett D, Bensinger E, Rani L, Sherkat Y, Zhao C, Helft Z, Roorda A, Green AJ, Sheehy CK

Spinal cord atrophy predicts progressive disease in relapsing multiple sclerosis.

Annals of neurology

Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, Mallott JM, Asteggiano C, Sacco S, Gundel TJ, Zhao C, Stern WA, Caverzasi E, Zhou Y, Gomez R, Ragan NR, Santaniello A, Zhu AH, Juwono J, Bevan CJ, Bove RM, Crabtree E, Gelfand JM, Goodin DS, Graves JS, Green AJ, Oksenberg JR, Waubant E, Wilson MR, Zamvil SS, University of California, San Francisco MS-EPIC Team, Cree BA, Hauser SL, Henry RG

Interocular Difference in Retinal Nerve Fiber Layer Thickness Predicts Optic Neuritis in Pediatric-Onset Multiple Sclerosis.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

Waldman AT, Benson L, Sollee JR, Lavery AM, Liu GW, Green AJ, Waubant E, Heidary G, Conger D, Graves J, Greenberg B

Optical coherence tomography in multiple sclerosis: A 3-year prospective multicenter study.

Annals of clinical and translational neurology

Paul F, Calabresi PA, Barkhof F, Green AJ, Kardon R, Sastre-Garriga J, Schippling S, Vermersch P, Saidha S, Gerendas BS, Schmidt-Erfurth U, Agoropoulou C, Zhang Y, Seifer G, Petzold A

AQP4-IgG-seronegative patient outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder.

Multiple sclerosis and related disorders

Marignier R, Pittock SJ, Paul F, Kim HJ, Bennett JL, Weinshenker BG, Wingerchuk DM, Green AJ, Fujihara K, Cutter G, Aktas O, Hartung HP, Drappa J, Ratchford JN, She D, Smith M, Rees W, Cimbora D, Katz E, Cree BAC, N-MOmentum study investigators

Astrocytic outer retinal layer thinning is not a feature in AQP4-IgG seropositive neuromyelitis optica spectrum disorders.

Journal of neurology, neurosurgery, and psychiatry

Lu A, Zimmermann HG, Specovius S, Motamedi S, Chien C, Bereuter C, Lana-Peixoto MA, Fontenelle MA, Ashtari F, Kafieh R, Dehghani A, Pourazizi M, Pandit L, D'Cunha A, Kim HJ, Hyun JW, Jung SK, Leocani L, Pisa M, Radaelli M, Siritho S, May EF, Tongco C, De Sèze J, Senger T, Palace J, Roca-Fernández A, Leite MI, Sharma SM, Stiebel-Kalish H, Asgari N, Soelberg KK, Martinez-Lapiscina EH, Havla J, Mao-Draayer Y, Rimler Z, Reid A, Marignier R, Cobo-Calvo A, Altintas A, Tanriverdi U, Yildirim R, Aktas O, Ringelstein M, Albrecht P, Tavares IM, Bichuetti DB, Jacob A, Huda S, Soto de Castillo I, Petzold A, Green AJ, Yeaman MR, Smith TJ, Cook L, Paul F, Brandt AU, Oertel FC, GJCF International Clinical Consortium for NMOSD

Retinal Optical Coherence Tomography in Neuromyelitis Optica.

Neurology(R) neuroimmunology & neuroinflammation

Oertel FC, Specovius S, Zimmermann HG, Chien C, Motamedi S, Bereuter C, Cook L, Lana Peixoto MA, Fontanelle MA, Kim HJ, Hyun JW, Palace J, Roca-Fernandez A, Leite MI, Sharma S, Ashtari F, Kafieh R, Dehghani A, Pourazizi M, Pandit L, D'Cunha A, Aktas O, Ringelstein M, Albrecht P, May E, Tongco C, Leocani L, Pisa M, Radaelli M, Martinez-Lapiscina EH, Stiebel-Kalish H, Siritho S, de Seze J, Senger T, Havla J, Marignier R, Calvo AC, Bichuetti D, Tavares IM, Asgari N, Soelberg K, Altintas A, Yildirim R, Tanriverdi U, Jacob A, Huda S, Rimler Z, Reid A, Mao-Draayer Y, Soto de Castillo I, Petzold A, Green AJ, Yeaman MR, Smith T, Brandt AU, Paul F

Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis.

JCI insight

Cruz-Herranz A, Oertel FC, Kim K, Cantó E, Timmons G, Sin JH, Devereux M, Baker N, Michel B, Schubert RD, Rani L, Cordano C, Baranzini SE, Green AJ

Artificial intelligence extension of the OSCAR-IB criteria.

Annals of clinical and translational neurology

Petzold A, Albrecht P, Balcer L, Bekkers E, Brandt AU, Calabresi PA, Deborah OG, Graves JS, Green A, Keane PA, Nij Bijvank JA, Sander JW, Paul F, Saidha S, Villoslada P, Wagner SK, Yeh EA, IMSVISUAL, ERN-EYE Consortium

Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE ε4 gene carriers.

Alzheimer's & dementia (Amsterdam, Netherlands)

Elahi FM, Ashimatey SB, Bennett DJ, Walters SM, La Joie R, Jiang X, Wolf A, Cobigo Y, Staffaroni AM, Rosen HJ, Miller BL, Rabinovici GD, Kramer JH, Green AJ, Kashani AH

The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies.

Neurology

Aytulun A, Cruz-Herranz A, Aktas O, Balcer LJ, Balk L, Barboni P, Blanco AA, Calabresi PA, Costello F, Sanchez-Dalmau B, DeBuc DC, Feltgen N, Finger RP, Frederiksen JL, Frohman E, Frohman T, Garway-Heath D, Gabilondo I, Graves JS, Green AJ, Hartung HP, Havla J, Holz FG, Imitola J, Kenney R, Klistorner A, Knier B, Korn T, Kolbe S, Krämer J, Lagrèze WA, Leocani L, Maier O, Martínez-Lapiscina EH, Meuth S, Outteryck O, Paul F, Petzold A, Pihl-Jensen G, Preiningerova JL, Rebolleda G, Ringelstein M, Saidha S, Schippling S, Schuman JS, Sergott RC, Toosy A, Villoslada P, Wolf S, Yeh EA, Yu-Wai-Man P, Zimmermann HG, Brandt AU, Albrecht P

Disability Outcomes in the N-MOmentum Trial of Inebilizumab in Neuromyelitis Optica Spectrum Disorder.

Neurology(R) neuroimmunology & neuroinflammation

Marignier R, Bennett JL, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk D, Fujihara K, Paul F, Cutter GR, Green AJ, Aktas O, Hartung HP, Lublin FD, Williams IM, Drappa J, She D, Cimbora D, Rees W, Smith M, Ratchford JN, Katz E, Cree BAC, N-MOmentum Study Investigators

Sensitivity analysis of the primary endpoint from the N-MOmentum study of inebilizumab in NMOSD.

Multiple sclerosis (Houndmills, Basingstoke, England)

Cree BA, Bennett JL, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk D, Fujihara K, Paul F, Cutter GR, Marignier R, Green AJ, Aktas O, Hartung HP, Williams IM, Drappa J, She D, Cimbora D, Rees W, Ratchford JN, Katz E

Underutilization of physical therapy for symptomatic women with MS during and following pregnancy.

Multiple sclerosis and related disorders

Block VJ, Mestas O, Anderson A, Singh J, Wylie L, Guo CY, Green AJ, Gelfand JM, Bove R

Retinal INL thickness in multiple sclerosis: a mere marker of neurodegeneration?

Annals of neurology

Cordano C, Yiu HH, Oertel FC, Gelfand JM, Hauser SL, Cree BAC, Green AJ

Neurite Orientation Dispersion and Density Imaging for Assessing Acute Inflammation and Lesion Evolution in MS.

AJNR. American journal of neuroradiology

Sacco S, Caverzasi E, Papinutto N, Cordano C, Bischof A, Gundel T, Cheng S, Asteggiano C, Kirkish G, Mallott J, Stern WA, Bastianello S, Bove RM, Gelfand JM, Goodin DS, Green AJ, Waubant E, Wilson MR, Zamvil SS, Cree BA, Hauser SL, Henry RG

Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.

Nature immunology

Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff SJ, Machado MR, Bedard C, Coronado PER, Jiang X, Wang J, Pleiss MA, Green AJ, Zamvil SS, Pico AR, Bruneau BG, Arkin MR, Akassoglou K

Importance of Not MSing Cerebral White Matter Disease in Patients with Inflammatory Bowel Disease.

Digestive diseases and sciences

Regner EH, Green AJ, Bain JL, Kattah MG, Mahadevan U

A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America

Ramesh A, Schubert RD, Greenfield AL, Dandekar R, Loudermilk R, Sabatino JJ, Koelzer MT, Tran EB, Koshal K, Kim K, Pröbstel AK, Banerji D, Guo CY, Green AJ, Bove RM, DeRisi JL, Gelfand JM, Cree BAC, Zamvil SS, Baranzini SE, Hauser SL, Wilson MR

Imaging correlates of visual function in multiple sclerosis.

PloS one

Caverzasi E, Cordano C, Zhu AH, Zhao C, Bischof A, Kirkish G, Bennett DJ, Devereux M, Baker N, Inman J, Yiu HH, Papinutto N, Gelfand JM, Cree BAC, Hauser SL, Henry RG, Green AJ

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.

Nature immunology

Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff SJ, Machado MR, Bedard C, Rios Coronado PE, Jiang X, Wang J, Pleiss MA, Green AJ, Zamvil SS, Pico AR, Bruneau BG, Arkin MR, Akassoglou K

Protective effects of 4-aminopyridine in experimental optic neuritis and multiple sclerosis.

Brain : a journal of neurology

Dietrich M, Koska V, Hecker C, Göttle P, Hilla AM, Heskamp A, Lepka K, Issberner A, Hallenberger A, Baksmeier C, Steckel J, Balk L, Knier B, Korn T, Havla J, Martínez-Lapiscina EH, Solà-Valls N, Manogaran P, Olbert ED, Schippling S, Cruz-Herranz A, Yiu H, Button J, Caldito NG, von Gall C, Mausberg AK, Stettner M, Zimmermann HG, Paul F, Brandt AU, Küry P, Goebels N, Aktas O, Berndt C, Saidha S, Green AJ, Calabresi PA, Fischer D, Hartung HP, Albrecht P

Fixational microsaccades: A quantitative and objective measure of disability in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Sheehy CK, Bensinger ES, Romeo A, Rani L, Stepien-Bernabe N, Shi B, Helft Z, Putnam N, Cordano C, Gelfand JM, Bove R, Stevenson SB, Green AJ

Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis.

Journal of neuroinflammation

Cruz-Herranz A, Dietrich M, Hilla AM, Yiu HH, Levin MH, Hecker C, Issberner A, Hallenberger A, Cordano C, Lehmann-Horn K, Balk LJ, Aktas O, Ingwersen J, von Gall C, Hartung HP, Zamvil SS, Fischer D, Albrecht P, Green AJ

Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial.

Lancet (London, England)

Cree BAC, Bennett JL, Kim HJ, Weinshenker BG, Pittock SJ, Wingerchuk DM, Fujihara K, Paul F, Cutter GR, Marignier R, Green AJ, Aktas O, Hartung HP, Lublin FD, Drappa J, Barron G, Madani S, Ratchford JN, She D, Cimbora D, Katz E

Early complement genes are associated with visual system degeneration in multiple sclerosis.

Brain : a journal of neurology

Fitzgerald KC, Kim K, Smith MD, Aston SA, Fioravante N, Rothman AM, Krieger S, Cofield SS, Kimbrough DJ, Bhargava P, Saidha S, Whartenby KA, Green AJ, Mowry EM, Cutter GR, Lublin FD, Baranzini SE, De Jager PL, Calabresi PA

Lessons from an unsuccessful therapeutic trial.

The Lancet. Neurology

Green AJ

Silent progression in disease activity-free relapsing multiple sclerosis.

Annals of neurology

Cree BAC, Hollenbach JA, Bove R, Kirkish G, Sacco S, Caverzasi E, Bischof A, Gundel T, Zhu AH, Papinutto N, Stern WA, Bevan C, Romeo A, Goodin DS, Gelfand JM, Graves J, Green AJ, Wilson MR, Zamvil SS, Zhao C, Gomez R, Ragan NR, Rush GQ, Barba P, Santaniello A, Baranzini SE, Oksenberg JR, Henry RG, Hauser SL

Association of Continuous Assessment of Step Count by Remote Monitoring With Disability Progression Among Adults With Multiple Sclerosis.

JAMA network open

Block VJ, Bove R, Zhao C, Garcha P, Graves J, Romeo AR, Green AJ, Allen DD, Hollenbach JA, Olgin JE, Marcus GM, Pletcher MJ, Cree BAC, Gelfand JM

Selective Estrogen Receptor Modulators Enhance CNS Remyelination Independent of Estrogen Receptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Rankin KA, Mei F, Kim K, Shen YA, Mayoral SR, Desponts C, Lorrain DS, Green AJ, Baranzini SE, Chan JR, Bove R

pRNFL as a marker of disability worsening in the medium/long term in patients with MS.

Neurology(R) neuroimmunology & neuroinflammation

Cordano C, Nourbakhsh B, Devereux M, Damotte V, Bennett D, Hauser SL, Cree BAC, Gelfand JM, Green AJ

Methods to Assess Ocular Motor Dysfunction in Multiple Sclerosis.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

Sheehy CK, Beaudry-Richard A, Bensinger E, Theis J, Green AJ

Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients.

mBio

Orrù CD, Soldau K, Cordano C, Llibre-Guerra J, Green AJ, Sanchez H, Groveman BR, Edland SD, Safar JG, Lin JH, Caughey B, Geschwind MD, Sigurdson CJ

Clinic to in-home telemedicine reduces barriers to care for patients with MS or other neuroimmunologic conditions.

Neurology(R) neuroimmunology & neuroinflammation

Bove R, Garcha P, Bevan CJ, Crabtree-Hartman E, Green AJ, Gelfand JM

Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity.

eLife

Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, Shiow LR, Kelley KW, Sadowski B, Timmons G, Pröbstel AK, Wright JN, Sin JH, Devereux M, Morrison DE, Chang SM, Sabeur K, Green AJ, Nave KA, Franklin RJ, Rowitch DH

Toward a low-cost, in-home, telemedicine-enabled assessment of disability in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Bove R, Bevan C, Crabtree E, Zhao C, Gomez R, Garcha P, Morrissey J, Dierkhising J, Green AJ, Hauser SL, Cree BA, Wallin MT, Gelfand JM

Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing.

JAMA neurology

Wilson MR, O'Donovan BD, Gelfand JM, Sample HA, Chow FC, Betjemann JP, Shah MP, Richie MB, Gorman MP, Hajj-Ali RA, Calabrese LH, Zorn KC, Chow ED, Greenlee JE, Blum JH, Green G, Khan LM, Banerji D, Langelier C, Bryson-Cahn C, Harrington W, Lingappa JR, Shanbhag NM, Green AJ, Brew BJ, Soldatos A, Strnad L, Doernberg SB, Jay CA, Douglas V, Josephson SA, DeRisi JL

Reduced contrast sensitivity among older women is associated with increased risk of cognitive impairment.

Annals of neurology

Ward ME, Gelfand JM, Lui LY, Ou Y, Green AJ, Stone K, Pedula KL, Cummings SR, Yaffe K

OCT is an alternative to MRI for monitoring MS - Commentary.

Multiple sclerosis (Houndmills, Basingstoke, England)

Green AJ

Rituximab before and during pregnancy: A systematic review, and a case series in MS and NMOSD.

Neurology(R) neuroimmunology & neuroinflammation

Das G, Damotte V, Gelfand JM, Bevan C, Cree BAC, Do L, Green AJ, Hauser SL, Bove R

Multicenter reliability of semiautomatic retinal layer segmentation using OCT.

Neurology(R) neuroimmunology & neuroinflammation

Oberwahrenbrock T, Traber GL, Lukas S, Gabilondo I, Nolan R, Songster C, Balk L, Petzold A, Paul F, Villoslada P, Brandt AU, Green AJ, Schippling S

Harnessing electronic medical records to advance research on multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Damotte V, Lizée A, Tremblay M, Agrawal A, Khankhanian P, Santaniello A, Gomez R, Lincoln R, Tang W, Chen T, Lee N, Villoslada P, Hollenbach JA, Bevan CD, Graves J, Bove R, Goodin DS, Green AJ, Baranzini SE, Cree BA, Henry RG, Hauser SL, Gelfand JM, Gourraud PA

Cell-based therapeutic strategies for multiple sclerosis.

Brain : a journal of neurology

Scolding NJ, Pasquini M, Reingold SC, Cohen JA

Infliximab for the treatment of CNS sarcoidosis: A multi-institutional series.

Neurology

Gelfand JM, Bradshaw MJ, Stern BJ, Clifford DB, Wang Y, Cho TA, Koth LL, Hauser SL, Dierkhising J, Vu N, Sriram S, Moses H, Bagnato F, Kaufmann JA, Ammah DJ, Yohannes TH, Hamblin MJ, Venna N, Green AJ, Pawate S

Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial.

Lancet (London, England)

Green AJ, Gelfand JM, Cree BA, Bevan C, Boscardin WJ, Mei F, Inman J, Arnow S, Devereux M, Abounasr A, Nobuta H, Zhu A, Friessen M, Gerona R, von Büdingen HC, Henry RG, Hauser SL, Chan JR

Remyelinating Pharmacotherapies in Multiple Sclerosis.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Bove RM, Green AJ

Systematic integration of biomedical knowledge prioritizes drugs for repurposing.

eLife

Himmelstein DS, Lizee A, Hessler C, Brueggeman L, Chen SL, Hadley D, Green A, Khankhanian P, Baranzini SE

Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis.

The Lancet. Neurology

Petzold A, Balcer LJ, Calabresi PA, Costello F, Frohman TC, Frohman EM, Martinez-Lapiscina EH, Green AJ, Kardon R, Outteryck O, Paul F, Schippling S, Vermersch P, Villoslada P, Balk LJ

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4.

Journal of visualized experiments : JoVE

Sagan SA, Cruz-Herranz A, Spencer CM, Ho PP, Steinman L, Green AJ, Sobel RA, Zamvil SS

T cells targeting neuromyelitis optica autoantigen aquaporin-4 cause paralysis and visual system injury.

Journal of nature and science

Cruz-Herranz A, Sagan SA, Sobel RA, Green AJ, Zamvil SS

Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.

Science translational medicine

Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, Seeley WW, Miller BL, Bigio E, Mesulam MM, Bogyo MS, Mackenzie IR, Staropoli JF, Cotman SL, Huang EJ, Gan L, Green AJ

Retinal thinning is uniquely associated with medial temporal lobe atrophy in neurologically normal older adults.

Neurobiology of aging

Casaletto KB, Ward ME, Baker NS, Bettcher BM, Gelfand JM, Li Y, Chen R, Dutt S, Miller B, Kramer JH, Green AJ

Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4.

Proceedings of the National Academy of Sciences of the United States of America

Sagan SA, Winger RC, Cruz-Herranz A, Nelson PA, Hagberg S, Miller CN, Spencer CM, Ho PP, Bennett JL, Levy M, Levin MH, Verkman AS, Steinman L, Green AJ, Anderson MS, Sobel RA, Zamvil SS

Whole-body positional manipulators for ocular imaging of anaesthetised mice and rats: a do-it-yourself guide.

BMJ open ophthalmology

Dietrich M, Cruz-Herranz A, Yiu H, Aktas O, Brandt AU, Hartung HP, Green A, Albrecht P

Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery.

eLife

Mei F, Lehmann-Horn K, Shen YA, Rankin KA, Stebbins KJ, Lorrain DS, Pekarek K, A Sagan S, Xiao L, Teuscher C, von Büdingen HC, Wess J, Lawrence JJ, Green AJ, Fancy SP, Zamvil SS, Chan JR

Long-term evolution of multiple sclerosis disability in the treatment era.

Annals of neurology

Cree BA, Gourraud PA, Oksenberg JR, Bevan C, Crabtree-Hartman E, Gelfand JM, Goodin DS, Graves J, Green AJ, Mowry E, Okuda DT, Pelletier D, von Büdingen HC, Zamvil SS, Agrawal A, Caillier S, Ciocca C, Gomez R, Kanner R, Lincoln R, Lizee A, Qualley P, Santaniello A, Suleiman L, Bucci M, Panara V, Papinutto N, Stern WA, Zhu AH, Cutter GR, Baranzini S, Henry RG, Hauser SL

Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Mei F, Mayoral SR, Nobuta H, Wang F, Desponts C, Lorrain DS, Xiao L, Green AJ, Rowitch D, Whistler J, Chan JR

Sex differences and subclinical retinal injury in pediatric-onset MS.

Multiple sclerosis (Houndmills, Basingstoke, England)

Graves JS, Chohan H, Cedars B, Arnow S, Yiu H, Waubant E, Green A

The APOSTEL recommendations for reporting quantitative optical coherence tomography studies.

Neurology

Cruz-Herranz A, Balk LJ, Oberwahrenbrock T, Saidha S, Martinez-Lapiscina EH, Lagreze WA, Schuman JS, Villoslada P, Calabresi P, Balcer L, Petzold A, Green AJ, Paul F, Brandt AU, Albrecht P

Timing of retinal neuronal and axonal loss in MS: a longitudinal OCT study.

Journal of neurology

Balk LJ, Cruz-Herranz A, Albrecht P, Arnow S, Gelfand JM, Tewarie P, Killestein J, Uitdehaag BM, Petzold A, Green AJ

Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study.

The Lancet. Neurology

Martinez-Lapiscina EH, Arnow S, Wilson JA, Saidha S, Preiningerova JL, Oberwahrenbrock T, Brandt AU, Pablo LE, Guerrieri S, Gonzalez I, Outteryck O, Mueller AK, Albrecht P, Chan W, Lukas S, Balk LJ, Fraser C, Frederiksen JL, Resto J, Frohman T, Cordano C, Zubizarreta I, Andorra M, Sanchez-Dalmau B, Saiz A, Bermel R, Klistorner A, Petzold A, Schippling S, Costello F, Aktas O, Vermersch P, Oreja-Guevara C, Comi G, Leocani L, Garcia-Martin E, Paul F, Havrdova E, Frohman E, Balcer LJ, Green AJ, Calabresi PA, Villoslada P

The challenge of comorbidity in clinical trials for multiple sclerosis.

Neurology

Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Reingold S, Cohen JA

Recommendations for observational studies of comorbidity in multiple sclerosis.

Neurology

Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Fiest K, Reider N, Reingold S, Cohen JA

Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis.

JAMA neurology

Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA, Hauser SL, Henry RG

Retinal damage and vision loss in African American multiple sclerosis patients.

Annals of neurology

Kimbrough DJ, Sotirchos ES, Wilson JA, Al-Louzi O, Conger A, Conger D, Frohman TC, Saidha S, Green AJ, Frohman EM, Balcer LJ, Calabresi PA

Encephalitis of unclear origin diagnosed by brain biopsy: a diagnostic challenge.

JAMA neurology

Gelfand JM, Genrich G, Green AJ, Tihan T, Cree BA

The best basic science paper in MS in 2013: Antimuscarinic therapies in remyelination.

Multiple sclerosis (Houndmills, Basingstoke, England)

Green AJ

Precision medicine in chronic disease management: The multiple sclerosis BioScreen.

Annals of neurology

Gourraud PA, Henry RG, Cree BA, Crane JC, Lizee A, Olson MP, Santaniello AV, Datta E, Zhu AH, Bevan CJ, Gelfand JM, Graves JS, Goodin DS, Green AJ, von Büdingen HC, Waubant E, Zamvil SS, Crabtree-Hartman E, Nelson S, Baranzini SE, Hauser SL

Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD.

The Journal of experimental medicine

Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, Kraft TW, Farese RV, Green A, Gan L

Spinal cord gray matter atrophy correlates with multiple sclerosis disability.

Annals of neurology

Schlaeger R, Papinutto N, Panara V, Bevan C, Lobach IV, Bucci M, Caverzasi E, Gelfand JM, Green AJ, Jordan KM, Stern WA, von Büdingen HC, Waubant E, Zhu AH, Goodin DS, Cree BA, Hauser SL, Henry RG

Magnetic resonance imaging correlates of clinical outcomes in early multiple sclerosis.

Multiple sclerosis and related disorders

Maghzi AH, Revirajan N, Julian LJ, Spain R, Mowry EM, Liu S, Jin C, Green AJ, McCulloch CE, Pelletier D, Waubant E

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.

Nature medicine

Mei F, Fancy SPJ, Shen YA, Niu J, Zhao C, Presley B, Miao E, Lee S, Mayoral SR, Redmond SA, Etxeberria A, Xiao L, Franklin RJM, Green A, Hauser SL, Chan JR

Retinal architecture and mfERG: Optic nerve head component response characteristics in MS.

Neurology

Schnurman ZS, Frohman TC, Beh SC, Conger D, Conger A, Saidha S, Galetta S, Calabresi PA, Green AJ, Balcer LJ, Frohman EM

Optic nerve head component responses of the multifocal electroretinogram in MS.

Neurology

Frohman TC, Beh SC, Saidha S, Schnurman Z, Conger D, Conger A, Ratchford JN, Lopez C, Galetta SL, Calabresi PA, Balcer LJ, Green AJ, Frohman EM

Microcystic inner nuclear layer abnormalities and neuromyelitis optica.

JAMA neurology

Gelfand JM, Cree BA, Nolan R, Arnow S, Green AJ

Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study.

The Lancet. Neurology

Saidha S, Sotirchos ES, Ibrahim MA, Crainiceanu CM, Gelfand JM, Sepah YJ, Ratchford JN, Oh J, Seigo MA, Newsome SD, Balcer LJ, Frohman EM, Green AJ, Nguyen QD, Calabresi PA

Microcystic macular oedema in multiple sclerosis is associated with disease severity.

Brain : a journal of neurology

Gelfand JM, Nolan R, Schwartz DM, Graves J, Green AJ

Will the real optic nerve sheath please stand up?

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

Teismann NA, Lenaghan P, Stein J, Green A

Switching multiple sclerosis patients with breakthrough disease to second-line therapy.

PloS one

Castillo-Trivino T, Mowry EM, Gajofatto A, Chabas D, Crabtree-Hartman E, Cree BA, Goodin DS, Green AJ, Okuda DT, Pelletier D, Zamvil SS, Vittinghoff E, Waubant E

Heterogeneous patterns of tissue injury in NARP syndrome.

Journal of neurology

Gelfand JM, Duncan JL, Racine CA, Gillum LA, Chin CT, Zhang Y, Zhang Q, Wong LJ, Roorda A, Green AJ

Optical coherence tomography in multiple sclerosis: a systematic review and meta-analysis.

The Lancet. Neurology

Petzold A, de Boer JF, Schippling S, Vermersch P, Kardon R, Green A, Calabresi PA, Polman C

Ocular pathology in multiple sclerosis: retinal atrophy and inflammation irrespective of disease duration.

Brain : a journal of neurology

Green AJ, McQuaid S, Hauser SL, Allen IV, Lyness R

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.

Human molecular genetics

Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, Radue EW, Lindberg RL, Uitdehaag BM, Johnson MR, Angelakopoulou A, Hall L, Richardson JC, Prinjha RK, Gass A, Geurts JJ, Kragt J, Sombekke M, Vrenken H, Qualley P, Lincoln RR, Gomez R, Caillier SJ, George MF, Mousavi H, Guerrero R, Okuda DT, Cree BA, Green AJ, Waubant E, Goodin DS, Pelletier D, Matthews PM, Hauser SL, Kappos L, Polman CH, Oksenberg JR

Pediatric multiple sclerosis.

NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics

Chabas D, Green AJ, Waubant E

Progressive multifocal leukoencephalopathy in a patient treated with natalizumab.

The New England journal of medicine

Langer-Gould A, Atlas SW, Green AJ, Bollen AW, Pelletier D